Community sources disagree on rarity (Common vs. Uncommon). Until an official note clarifies it, we list it as Unconfirmed. Gameplay effect is consistent across sources.
Unstable Transfusion gives each hit a 35% chance to add a Bloodmark stack. Bloodmark stores pending damage, normally resolves after its timer, and resolves immediately when the stored amount becomes lethal.
Unlocked by default. No quest or shrine requirement—this item is in your pool from the start.
Also applies Bloodmark (and boosts on-hit odds). Together they ramp stacks quickly on bosses.
Pair Bloodmark stacking with sustain so you can stay aggressive while face-tanking crowds.
Prevents chip damage from ending your streaks as you farm stacks.
Once stacks are rolling, swap to heavier single-target damage (or keep stacking) to finish bosses quickly.
v1.0.49 (Dec 25, 2025): the official Christmas Patch increased Bloodmark chance from 27% to 35%. The current values throughout this page use the post-patch 35% chance.
35% per hit.
Yes. More stacks = faster kills, especially on elites/bosses.
It’s available by default.