Unstable Transfusion item icon

Unstable Transfusion

⭐ RARITY: UNCONFIRMED
Effect: 35% chance to apply Bloodmark on hit (stacks). Browse all items to see more on-hit effects.
Heads-up

Community sources disagree on rarity (Common vs. Uncommon). Until an official note clarifies it, we list it as Unconfirmed. Gameplay effect is consistent across sources.

Proc Chance
35%
Stacks?
Yes
Unlock
Default
Rarity
Unconfirmed

🧪 What Bloodmark Does

Unstable Transfusion gives each hit a 35% chance to add a Bloodmark stack. Bloodmark stores pending damage, normally resolves after its timer, and resolves immediately when the stored amount becomes lethal.

Key Takeaways

Read the complete Bloodmark mechanics and build guide →

🔓 Unlock Method

Unlocked by default. No quest or shrine requirement—this item is in your pool from the start.

🔗 Best Synergies & Builds

Core Item Synergies

Bloody Cleaver icon EXCELLENT

Bloody Cleaver

Also applies Bloodmark (and boosts on-hit odds). Together they ramp stacks quickly on bosses.

Slurp Gloves icon GOOD

Lifesteal Items

Pair Bloodmark stacking with sustain so you can stay aggressive while face-tanking crowds.

Medkit icon GOOD

Regen / Medkit

Prevents chip damage from ending your streaks as you farm stacks.

Weapons that Stack Fast

Katana

Katana

High hit frequency to roll that 35% often.

Aura

Aura

Persistent damage ticks = constant stack attempts.

Lightning Staff

Lightning Staff

Chains through packs to seed stacks broadly.

Tip

Once stacks are rolling, swap to heavier single-target damage (or keep stacking) to finish bosses quickly.

📋 Patch & Meta Notes

v1.0.49 (Dec 25, 2025): the official Christmas Patch increased Bloodmark chance from 27% to 35%. The current values throughout this page use the post-patch 35% chance.

❓ FAQ

What’s the proc chance?

35% per hit.

Does Bloodmark stack?

Yes. More stacks = faster kills, especially on elites/bosses.

How do I unlock it?

It’s available by default.