Unstable Transfusion item icon

Unstable Transfusion

⭐ RARITY: UNCONFIRMED
Effect: 27% chance to apply Bloodmark on hit (stacks). Browse all items to see more on-hit effects.
Heads-up

Community sources disagree on rarity (Common vs. Uncommon). Until an official note clarifies it, we list it as Unconfirmed. Gameplay effect is consistent across sources.

Proc Chance
27%
Stacks?
Yes
Unlock
Default
Rarity
Unconfirmed

🧪 What Bloodmark Does

Unstable Transfusion introduces the Bloodmark status. Each hit has a 27% chance to add a stack; more stacks = faster melts on elites and bosses. It’s especially potent in builds that hit rapidly or constantly apply contact damage.

Key Takeaways

🔓 Unlock Method

Unlocked by default. No quest or shrine requirement—this item is in your pool from the start.

🔗 Best Synergies & Builds

Core Item Synergies

Bloody Cleaver icon EXCELLENT

Bloody Cleaver

Also applies Bloodmark (and boosts on-hit odds). Together they ramp stacks quickly on bosses.

Slurp Gloves icon GOOD

Lifesteal Items

Pair Bloodmark stacking with sustain so you can stay aggressive while face-tanking crowds.

Medkit icon GOOD

Regen / Medkit

Prevents chip damage from ending your streaks as you farm stacks.

Weapons that Stack Fast

Katana

Katana

High hit frequency to roll that 27% often.

Aura

Aura

Persistent damage ticks = constant stack attempts.

Lightning Staff

Lightning Staff

Chains through packs to seed stacks broadly.

Tip

Once stacks are rolling, swap to heavier single-target damage (or keep stacking) to finish bosses quickly.

📋 Patch & Meta Notes

Recent updates around v1.0.12 (Oct 2025) curbed extreme execute/black-hole metas. There’s no direct note of Unstable Transfusion being changed in major coverage; its role as a stacker remains intact. Keep an eye on official notes for any future tuning.

❓ FAQ

What’s the proc chance?

27% per hit.

Does Bloodmark stack?

Yes. More stacks = faster kills, especially on elites/bosses.

How do I unlock it?

It’s available by default.