Poison Flask
Short-Range DoT Sustain Weapon • Strong on Amog with the right items
🧪 Weapon Overview
Poison Flask throws a short-arc bottle that shatters into a poison cloud. Enemies inside are poisoned and take damage over time. The weapon’s base hit is only 1 damage, so its performance comes from stacking Duration/Quantity/Size and leveraging item synergies rather than raw burst.
✅ Strengths
- Reliable area denial via lingering poison clouds
- Excellent sustain with lifesteal builds (see Bloody Tome)
- Scales well with Duration, Size, and Projectile Count
- Pairs naturally with Amog’s poison-spread passive
❌ Weaknesses
- Base damage is 1; slow to start
- Very short range; demands constant movement
- No native Crit upgrades; lower peak DPS than crit metas
- Delayed kills can slow XP/loot collection without support
🔓 How to Unlock Poison Flask
Play on the Desert Map
Queue a Desert run. Scorpionussy is a Desert-exclusive miniboss that can spawn during the run.
Defeat Scorpionussy
Build enough safe damage to down it consistently. Repeat across runs; the count is cumulative.
Enjoy the Unlock
Once you’ve logged three kills, Poison Flask becomes available in your weapon pool.
⚙️ Core Mechanics
🎯 Attack Pattern
Throws a bottle in a short arc. On impact it creates a poison cloud that inflicts a damage-over-time (DoT) effect. Stacking Duration, Size, and Projectile Count increases coverage and total ticks.
📊 Upgrades (5)
- Damage — increases base hit and DoT contribution
- Duration — longer-lasting clouds/status
- Projectile Count — more bottles per cycle
- Projectile Speed — starts at 16 (increased from 12), with upgrades adding further speed
- Size — larger explosion/cloud area
☠️ Amog Synergy
Amog starts with Poison Flask. His passive Plague makes poisoned enemies explode on death, spreading poison to nearby foes — a natural amplifier for this weapon’s coverage and sustain playstyle.
How to Unlock Amog
🎒 Items & Synergies (Verified)
🧀 Moldy Cheese
Effect: 40% chance to apply poison on hit.
Notes: Multiple copies grant additional independent chances (separate rolls) rather than simply adding a single % number.
💡 Overpowered Lamp
Effect: Grants an extra proc roll for on-hit effects (e.g., a second roll for Moldy Cheese’s 40%).
Impact: Greatly increases practical poison application rate; two 40% rolls ≈ 64% chance.
😷 Gas Mask
Effect: Grants Armor and Lifesteal for every poisoned enemy (dynamic).
Why good here: Poison Flask quickly fills the screen with poisoned targets, boosting both defense and sustain.
⚡ Lightning Orb
Effect: 25% chance to summon lightning on hit; lightning can stun enemies.
Synergy: Adds control; pairs well with Lightning Staff or any fast-hitting setup.
🩸 Bloody Tome (Lifesteal)
Effect: Chance to heal 1 HP when you hit an enemy. At 100%+ lifesteal, healing per hit is guaranteed (and can exceed 1 at very high values).
Interaction: Frequent poison ticks help trigger steady healing.
🪞 Mirror & 🧸 Kevin (advanced)
Status: Patch v1.0.7 removed the “true invincibility” exploit. The combo can still produce strong survivability windows but no longer grants automatic immortality.
🏗️ Practical Build Path
🌱 Early Game (survive & stabilize)
- Pick a ranged support (e.g., Lightning Staff or Aura) to cover distance and speed up clears.
- Prioritize Bloody Tome levels; work toward 100% lifesteal.
- Take Duration/Size/Quantity on Poison Flask to expand coverage.
- Stay mobile; your throw range is short.
⚔️ Mid Game (synergy online)
- Add Moldy Cheese and Overpowered Lamp to accelerate poison application.
- Include Gas Mask for defensive scaling as screens fill with poisoned enemies.
- Projectile Speed helps safely connect more throws.
🔥 Late Game (stack and sustain)
- Keep stacking Duration/Quantity/Size; damage grows with total ticks on screen.
- Use Lightning Orb for extra control (stuns) in dense waves.
- Maintain movement patterns; let poison churn while you kite.
📋 Tome Priority (general)
- High: Duration, Projectile Count, Size
- Helpful: Projectile Speed, Damage
- Defensive / Scaling: Bloody Tome (lifesteal), XP Tome situationally (note: XP Tome was nerfed to 7% in v1.0.12)
⚔️ Strategy & Tactics
🎯 Golden Rule: Keep Moving
🌀 Kiting Loop
- Loop around groups to lay overlapping poison clouds.
- Funnel enemies through chokepoints to maximize time in poison.
- Let kills chain via Amog’s Plague (if playing Amog).
👹 Boss Tips
- Keep poison uptime high; circle-kite to avoid burst.
- Lifesteal builds can out-heal chip damage while DoT works.
🔗 Useful Weapon Pairings
⚡ Lightning Staff
Chains between enemies for safe wave thinning. Stuns come from Lightning Orb, not the staff itself.
🌀 Aura
Ambient damage while you kite; helps pre-soften packs before they reach Flask range.
🦴 Bone
Bounces and extra projectiles help pick off stragglers at range.
❌ Avoid
- Setups that force you to stand still
- All short-range picks with no ranged support
📜 Version History & Meta Notes
✅ Patch v1.0.49 (Dec 25, 2025)
Current statThe current initial Projectile Speed is 16, improving bottle travel before any Projectile Speed upgrades.
🔄 Patch v1.0.12 (Oct 8, 2025)
Earlier patchFinal Swarm redesigned with tougher ghost waves; reduces low-FPS “lightshow” metas and tightens leaderboard integrity.
XP Tome reduced from 9% → 7% per level.
General fixes improved performance in heavy particle scenarios. (Not a Poison-Flask-specific buff.)
🔄 Patch v1.0.7 (Sep 29, 2025)
PreviousKevin no longer grants true invincibility via Mirror i-frame chaining. Survivability builds still exist, but the “immortal” loop was fixed.
❓ Frequently Asked Questions
Short answer: It can clear content consistently with proper items, but it’s rarely used for top scores compared to crit-scaling options.
Yes, but it’s best on Amog thanks to Plague (poison spread on death). Others should add strong ranged support to compensate for the short range.
Bloody Tome makes hits heal you. At 100% lifesteal, each hit heals 1 HP; poison ticks contribute many small “hits,” yielding steady healing.
Lightning Staff for hands-off chaining. Add Lightning Orb if you want stuns; the stun comes from the Orb, not the Staff itself.
⚖️ Summary
When to pick Poison Flask
- You enjoy DoT/sustain gameplay and constant kiting
- You plan to stack Duration/Size/Quantity and run lifesteal
- You’re playing Amog (best synergy via Plague)
When to skip
- You need instant burst or a crit-centric build
- You dislike close-range positioning
- You’re pushing for world-class leaderboard scores
Overall Role
Wins by coverage and uptime rather than raw burst.
Skill Ceiling
Positioning and itemization matter a lot due to short range.
Investment
Shines with specific synergies (Moldy Cheese, Lamp, Gas Mask, Bloody Tome).
Fun Factor
Extremely satisfying for DoT fans; slow start for everyone else.
